RealLine HPV HCR Screen

RealLine HPV HCR Screen

REF: VBD8444-R

The RealLine HPV HCR Screen kit is intended for the sensitive detection of 14 common high risk Genotypes of the Human Papillomavirus HPV.

All components are lyophilized and ready-to use.

This product is for General Laboratory Use (GLU)

 

 

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Description

More than 100 different Human Papilloma Viruses HPV are detected nowadays and some of these types are more likely to develop cancer in human beings. Those are  referred as “high carcinogenic risk”  or “high risk types” HPV and they are known to cause the vast majority of cervical cancers which cause death in women with an annual incidence of around half a million and a mortality of almost 50 %. But the persistent infection has also been linked to cancer of the oropharynx, larynx, vulva, vagina, penis, and anus.

The RealLine HPV HCR Screen kit detects following HPV genotypes in two tubes of mastermix:
16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66 and 68.

For optimal results please always use the RealLine Internal Control. In case you do not use RealLine Extraction kits, order RealLine Internal Control (REF VBC8881-R) seperately.

Sample Material

  • Scrapings of the epithelial cells
  • Biopsies

Detection Channels

  • FAM (495 – 520 nm) for Internal Control (IC)
  • HEX (535 – 554 nm) for the registration of DNA signals for high carcinogenic types of HPV
  • ROX (575 – 602 nm) for the registration of DNA signals for high carcinogenic types of HPV

Components

  • Ready Master Mix No.1 (RMM 1), lyophilized, 96 test-tubes
  • Ready Master Mix No.2 (RMM 2), lyophilized, 96 test-tubes
  • Positive Control Sample (PC)